Rosehip ( Rosa canina ) extracts prevent AKT and MAPK‐mediated cell proliferation in triple negative breast cancer cells
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چکیده
منابع مشابه
Thermal degradation kinetics of ascorbic acid, thiamine and riboflavin in rosehip (Rosa canina L) nectar
Rosehip is a good source of some biologically active compounds. The main importance of rosehip is its high composition of vitamin C and rutin (vitamin P) and high content of pectins, fatty acids, sugars, organic acids, phenolic components, lycopene, carotene with activity of vitamin A and group B vitamins, tannins, carotenoids, minerals (particularly K and P) macroand microelements (Tuer & Russ...
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Background: Triple-negative breast cancer (TNBC) is treated with highly aggressive non-targeted chemotherapies. Safer and more effective therapeutic approaches than those currently in use are needed. Natural pomegranate peel extract (PPE) has recently been found to inhibit breast cancer progression; however, its mechanisms of action remain unclear. We hypothesized that transcriptional chan...
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Breast cancer is the most prevalent cancer in women. Although the survival rate of breast cancer has improved steadily in the past two decades, over 40,000 women die from breast cancer related complications each year. The heterogeneity of breast cancer makes the treatment of different subtypes difficult (Gonzalez-Angulo et al., 2007; Perez et al., 2010). Triple negative breast cancer (TNBC) is ...
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Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...
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Cadmium (Cd) is a carcinogenic metal which is implicated in breast cancer by epidemiological studies. It is reported to promote breast cancer cell growth in vitro through membrane receptors. The study described here examined Cd-mediated growth of non-metastatic human breast cancer derived cells that lack receptors for estrogen, progesterone, and HER2. Treatment of triple-negative HCC 1937 cells...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2017
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.31.1_supplement.775.18